ca articles - Grup de recerca SINTCARB - Síntesis Orgànica Estereoselectiva articles Tue, 23 Apr 2024 07:43:30 +0000 Tue, 23 Apr 2024 07:43:30 +0000 Houdini 2 (https://houdini.antaviana.cat/) / Targeting Dihydroceramide Desaturase 1 (Des1): Syntheses of Ceramide Analogues with a Rigid Scaffold, Inhibitory Assays, and AlphaFold2-Assisted Structural Insights Reveal Cyclopropenone PR280 as a Potent Inhibitor Tue, 23 Apr 2024 07:43:30 +0000 http://www.sintcarb.urv.cat/ca/articles/6/targeting-dihydroceramide-desaturase-1-des1-syntheses-of-ceramide-analogues-with-a-rigid-scaffold-inhibitory-assays-and-alphafold2-assisted-structural-insights-reveal-cyclopropenone-pr280-as-a-potent-inhibitor http://www.sintcarb.urv.cat/ca/articles/6 0 Probing Site-Selective Conjugation Chemistries for the Construction of Homogeneous Synthetic Glycodendriproteins Fri, 29 Apr 2022 10:12:59 +0000 http://www.sintcarb.urv.cat/ca/articles/5/probing-site-selective-conjugation-chemistries-for-the-construction-of-homogeneous-synthetic-glycodendriproteins http://www.sintcarb.urv.cat/ca/articles/5 0 Revealing 2-Dimethylhydrazino-2-alkyl alkynyl sphingosine derivatives as Sphingosine Kinase 2 inhibitors: some hints on the structural basis for selective inhibition Fri, 29 Apr 2022 10:13:53 +0000 http://www.sintcarb.urv.cat/ca/articles/4/revealing-2-dimethylhydrazino-2-alkyl-alkynyl-sphingosine-derivatives-as-sphingosine-kinase-2-inhibitors-some-hints-on-the-structural-basis-for-selective-inhibition http://www.sintcarb.urv.cat/ca/articles/4 0 Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage Wed, 24 Apr 2019 14:16:19 +0000 http://www.sintcarb.urv.cat/ca/articles/3/structure-based-design-of-potent-tumor-associated-antigens-modulation-of-peptide-presentation-by-single-atom-o-s-or-o-se-substitutions-at-the-glycosidic-linkage http://www.sintcarb.urv.cat/ca/articles/3 0 Trifluoromethylation of Electron-Rich Alkenyl Iodides with Fluoroform-Derived "Ligandless" CuCF3 Wed, 24 Apr 2019 14:07:24 +0000 http://www.sintcarb.urv.cat/ca/articles/2/trifluoromethylation-of-electron-rich-alkenyl-iodides-with-fluoroform-derived-ligandless-cucf3 http://www.sintcarb.urv.cat/ca/articles/2 0